Health Equity in Focus delves into the intricate dynamics of global health, examining how historical legacies continue to shape present-day realities in the Global South. Global health institutions, when failing to address deep-rooted issues, can perpetuate inequalities between North and South. Across various episodes, we explore issues like the implications of intellectual property to access to medicines, the use of policy space through TRIPS flexibilities, international regulatory standards, the intersection of biological diversity with health, and developments regarding these topics in international fora, through an equity perspective.