The manifesto discusses the importance of biodiversity, the interconnectedness of the health of the Earth and human health, the impact of climate change, and the need for ecofeminist economics of giving and care. It also emphasizes the importance of seed freedom and biodiversity as the foundation of food freedom and climate resilience. The manifesto calls for a global transition to biodiverse and local food and farming systems for mitigating and adapting to climate change, ensuring food sovereignty, the overall health of ecosystems and people, the generation of livelihoods and healthy economies, and the creation of equity and justice.